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Myoma of UterusXu Hong2003-11-31Synonymsleiomyoma of uterusleiomyomasfibromyomasmyofibromasfibroidsfibromasmyomas2003-11-32IncidenceMost common solid pelvic tumorsDevelop in 2025% of women duringreproductive years3050 years old2003-11-33Correlative FactorsAn estrogenic milieu may be necessaryProgesterone functionestrogenpubertymenopauseprogesteroneGrowth factor and their receptorepithelial growth factorEGFInsulin-like growth factorIGFplatelet-derived growth factor2003-11-34Pathology2003-11-35Gross AppearanceRare only a singleusually many existWell-circumscribednonencapsulatedpseudocapsuleA pseudocapsule is present.The consistency is usually firm or even hardexcept when degeneration or hemorrhage hasoccurred.colorlight gray or pinkish whitecut sectionan intertwining pattern ora whorl-like arrangementbulgy2003-11-36Smooth muscle tumors of the uterus are oftenmultiple. Seen here are submucosal, intramural,and subserosal leiomyomata of the uterus.2003-11-37Microscopic AppearanceCompositionsmooth muscleconnective tissueThe nonstriated muscle fibers are arrangedin bundles of various sizes that run inmultiple directions.2003-11-38Classification1According to growth location Myomas on the body of uterus90% Myomas on the cervix of uterus10%2003-11-39Classification ...


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